ChromSword - HPLC method development
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What is the main advantage of ChromSword compared to other approaches?

Most available solutions focus on individual parts of HPLC method development, such as:

  • simulation and modeling
  • statistical optimization (DoE)
  • data analysis

These tools are useful, but their applicability is often limited to specific stages of the workflow.

ChromSword is designed differently. It supports the complete HPLC method lifecycle, including:

  • initial screening
  • method development
  • optimization
  • improvement of existing methods
  • robustness evaluation

Instead of assisting with separate tasks, ChromSword provides a continuous, connected workflow that leads from the first experiment to a final, robust analytical method.

Related FAQs

Unlike simulation tools that rely on initial data to predict peak behavior, ChromSword performs real experimental screening. It builds separations from scratch, successfully resolving complex, unknown, or overlapping mixtures.

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DoE tools require a well-defined starting method and experimental space to study parameter influences. In contrast, ChromSword uses adaptive, real-time feedback to develop methods dynamically without predefined designs, making it ideal for complex, unknown separations.

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Unlike general modeling tools that require well-resolved peaks and reliable input data to predict retention behavior, ChromSword relies on real experimental method development. It works directly with unresolved chromatograms, adapting dynamically to complex, unknown samples.

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Unlike limited, traditional HPLC tools (Simulation, DoE, Modeling) that require a pre-existing starting method, ChromSword provides full end-to-end automation and direct instrument control. It natively handles unresolved peaks, complex/unknown samples, and large molecule chemistry via dynamic, self-learning experimental optimization.

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